Chemical crosslinkers enhance detection of receptor interactomes

Receptor function is dependent on interaction with various intracellular proteins that ensure the localization and signaling of the receptor. While a number of approaches have been optimized for the isolation, purification, and proteomic characterization of receptor-protein interaction networks (int...

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Bibliographic Details
Main Authors: Brian A Corgiat, Jacob C Nordman, Nadine eKabbani
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00171/full