Dual Induction of New Microbial Secondary Metabolites by Fungal Bacterial Co-cultivation
The frequent re-isolation of known compounds is one of the major challenges in drug discovery. Many biosynthetic genes are not expressed under standard culture conditions, thus limiting the chemical diversity of microbial compounds that can be obtained through fermentation. On the other hand, the co...
Main Authors: | Jennifer Wakefield, Hossam M. Hassan, Marcel Jaspars, Rainer Ebel, Mostafa E. Rateb |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2017-07-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fmicb.2017.01284/full |
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