Solution phase synthesis of short oligoribonucleotides on a precipitative tetrapodal support

An effective method for the synthesis of short oligoribonucleotides in solution has been elaborated. Novel 2'-O-(2-cyanoethyl)-5'-O-(1-methoxy-1-methylethyl) protected ribonucleoside 3'-phosphoramidites have been prepared and their usefulness as building blocks in RNA synthesis on a s...

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Bibliographic Details
Main Authors: Alejandro Gimenez Molina, Amit M. Jabgunde, Pasi Virta, Harri Lönnberg
Format: Article
Language:English
Published: Beilstein-Institut 2014-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.10.237