Extracellular Collagen VI Has Prosurvival and Autophagy Instructive Properties in Mouse Fibroblasts

Extracellular Collagen VI Has Prosurvival and Autophagy Instructive Properties in Mouse Fibroblasts

Collagen VI (ColVI) is an abundant and distinctive extracellular matrix protein secreted by fibroblasts in different tissues. Human diseases linked to mutations on ColVI genes are primarily affecting skeletal muscle due to non-cell autonomous myofiber defects. To date, it is not known whether and ho...

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Bibliographic Details
Main Authors: Silvia Castagnaro, Martina Chrisam, Matilde Cescon, Paola Braghetta, Paolo Grumati, Paolo Bonaldo
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Physiology
Subjects:
collagen VI
autophagy
mitophagy
apoptosis
fibroblasts
lysosomes
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01129/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01129/full

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