Targeting of the MYCN protein with small molecule c-MYC inhibitors.

Targeting of the MYCN protein with small molecule c-MYC inhibitors.

Members of the MYC family are the most frequently deregulated oncogenes in human cancer and are often correlated with aggressive disease and/or poorly differentiated tumors. Since patients with MYCN-amplified neuroblastoma have a poor prognosis, targeting MYCN using small molecule inhibitors could r...

Full description

Bibliographic Details
Main Authors: Inga Müller, Karin Larsson, Anna Frenzel, Ganna Oliynyk, Hanna Zirath, Edward V Prochownik, Nicholas J Westwood, Marie Arsenian Henriksson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4032254?pdf=render

Internet

http://europepmc.org/articles/PMC4032254?pdf=render

Similar Items