Loop dynamics of thymidine diphosphate-rhamnose 3′-O-methyltransferase (CalS11), an enzyme in calicheamicin biosynthesis

Structure analysis and ensemble refinement of the apo-structure of thymidine diphosphate (TDP)-rhamnose 3′-O-methyltransferase reveal a gate for substrate entry and product release. TDP-rhamnose 3′-O-methyltransferase (CalS11) catalyses...

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Bibliographic Details
Main Authors: Lu Han, Shanteri Singh, Jon S. Thorson, George N. Phillips Jr.
Format: Article
Language:English
Published: AIP Publishing LLC and ACA 2016-01-01
Series:Structural Dynamics
Online Access:http://dx.doi.org/10.1063/1.4941368