Combination of Genomic and Transcriptomic Approaches Highlights Vascular and Circadian Clock Components in Multiple Sclerosis

Combination of Genomic and Transcriptomic Approaches Highlights Vascular and Circadian Clock Components in Multiple Sclerosis

Aiming at exploring vascular components in multiple sclerosis (MS) with brain outflow disturbance, we combined transcriptome analysis in MS internal jugular vein (IJV) wall with WES in MS families with vertical transmission of disease. Main results were the differential expression in IJV wall of 16...

Full description

Bibliographic Details
Main Authors: Chiara Scapoli, Nicole Ziliotto, Barbara Lunghi, Erica Menegatti, Fabrizio Salvi, Paolo Zamboni, Marcello Baroni, Francesco Mascoli, Francesco Bernardi, Giovanna Marchetti
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
vascular components
GWAS
transcriptomics
WES
rare variants
Online Access:https://www.mdpi.com/1422-0067/23/1/310

Internet

https://www.mdpi.com/1422-0067/23/1/310

Similar Items