Tissue Levels of Flurbiprofen in the Rat Plantar Heel after Short-Duration Topical Iontophoresis Are Sufficient to Induce Pharmacodynamic Responses to Local Pain Stimuli

Tissue Levels of Flurbiprofen in the Rat Plantar Heel after Short-Duration Topical Iontophoresis Are Sufficient to Induce Pharmacodynamic Responses to Local Pain Stimuli

The objective of this study was to investigate the topical iontophoresis of flurbiprofen (FBF) as a means to enhance its local bioavailability and thereby provide an improved and targeted treatment of plantar heel pain. Initial in vitro experiments using porcine ear skin investigated iontophoretic t...

Volledige beschrijving

Bibliografische gegevens
Hoofdauteurs: Yilu Cai, Ye Zhou, Peiyan Zhang, Yogeshvar N. Kalia, Tais Gratieri, Yong Chen
Formaat: Artikel
Taal:English
Gepubliceerd in: MDPI AG 2020-06-01
Reeks:Pharmaceutics
Onderwerpen:
flurbiprofen
iontophoresis
plantar heel pain
local delivery
Online toegang:https://www.mdpi.com/1999-4923/12/7/608

Internet

https://www.mdpi.com/1999-4923/12/7/608

Gelijkaardige items