Pitavastatin ameliorates myocardial damage by preventing inflammation and collagen deposition via reduced free radical generation in isoproterenol-induced cardiomyopathy

Pitavastatin inhibits 3 hydroxy 3 methyl glutaryl coenzyme A (HMGCoA) reductase enzyme, preventing cholesterol synthesis along with elevating high density apolipoprotein A1 (Apo-A1). The present study was designed to evaluate cardioprotective potential of pitavastatin at 1 mg/kg/day and 3 mg/kg/day...

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Bibliographic Details
Main Authors: Ramsha Iqbal, Md Sayeed Akhtar, Md Quamrul Hassan, Zeeba Jairajpuri, Mohd. Akhtar, Abul Kalam Najmi
Format: Article
Language:English
Published: Taylor & Francis Group 2019-07-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2018.1501059