Mechanical overload-induced release of extracellular mitochondrial particles from tendon cells leads to inflammation in tendinopathy

Abstract Tendinopathy is one of the most common musculoskeletal diseases, and mechanical overload is considered its primary cause. However, the underlying mechanism through which mechanical overload induces tendinopathy has not been determined. In this study, we identified for the first time that te...

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Bibliographic Details
Main Authors: Ziming Chen, Mengyuan Li, Peilin Chen, Andrew Tai, Jiayue Li, Euphemie Landao Bassonga, Junjie Gao, Delin Liu, David Wood, Brendan F. Kennedy, Qiujian Zheng, Ming H. Zheng
Format: Article
Language:English
Published: Nature Publishing Group 2024-03-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-024-01183-5