Therapeutics That Promote Sympathetic Reinnervation Modulate the Inflammatory Response After Myocardial Infarction

Therapeutics That Promote Sympathetic Reinnervation Modulate the Inflammatory Response After Myocardial Infarction

Summary: Myocardial infarction (MI) triggers an inflammatory response that transitions from pro-inflammatory to reparative over time. Restoring sympathetic nerves in the heart after MI prevents arrhythmias. This study investigated if reinnervation altered the immune response after MI. This study use...

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Bibliographic Details
Main Authors: Joseph J. Sepe, PhD, Ryan T. Gardner, PhD, Matthew R. Blake, BS, Deja M. Brooks, BS, Melanie A. Staffenson, BS, Courtney B. Betts, PhD, Sam Sivagnanam, MS, William Larson, BS, Sushil Kumar, PhD, Richard G. Bayles, PhD, Haihong Jin, PhD, Michael S. Cohen, PhD, Lisa M. Coussens, PhD, Beth A. Habecker, PhD
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:JACC: Basic to Translational Science
Subjects:
inflammation
macrophages
multiplex IHC
myocardial infarction
sympathetic nervous system
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X22001462

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http://www.sciencedirect.com/science/article/pii/S2452302X22001462

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