Circulating markers of microbial translocation and host response to bacteria with risk of colorectal cancer: a prospective, nested case-control study in menResearch in context

Summary: Background: Gut microbial dysbiosis contributes to colorectal cancer (CRC) pathogenesis, possibly mediated in part by increased intestinal permeability to endotoxin lipopolysaccharide (LPS), microbial translocation, and subsequent endotoxemia and inflammation. However, epidemiologic eviden...

Full description

Bibliographic Details
Main Authors: Mengyao Shi, Xiaoyu Zong, Jinhee Hur, Brenda M. Birmann, Otoniel Martinez-Maza, Marta Epeldegui, Andrew T. Chan, Edward L. Giovannucci, Yin Cao
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396423001317