Glucocorticoid receptor activation reduces food intake independent of hyperglycemia in zebrafish

Abstract Chronic cortisol exposure suppresses food intake in fish, but the central mechanism(s) involved in appetite regulation are unclear. Stress and the associated increase in cortisol levels increase hepatic gluconeogenesis, leading to hyperglycemia. As hyperglycemia causes a reduction in food i...

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Bibliographic Details
Main Authors: Niepukolie Nipu, Femilarani Antomagesh, Erin Faught, Mathilakath M. Vijayan
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-19572-z