Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions

Summary: Targeted genome editing holds great promise in biology. However, efficient genome modification, including gene knock-in (KI), remains an unattained goal in multiple cell types and loci due to poor transfection efficiencies and low target genes expression, impeding the positive selection of...

Full description

Bibliographic Details
Main Authors: Virginie Deleuze, Leonor Garcia, Betty Rouaisnel, Mohammad Salma, Alexia Kinoo, Charlotte Andrieu-Soler, Eric Soler
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223017182