The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2

The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2

Summary: The redox regulator NRF2 becomes activated upon oxidative and electrophilic stress and orchestrates a response program associated with redox regulation, metabolism, tumor therapy resistance, and immune suppression. Here, we describe an unrecognized link between the integrated stress respons...

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Bibliographic Details
Main Authors: Julia Katharina Charlotte Kreß, Christina Jessen, Anita Hufnagel, Werner Schmitz, Thamara Nishida Xavier da Silva, Ancély Ferreira dos Santos, Laura Mosteo, Colin R. Goding, José Pedro Friedmann Angeli, Svenja Meierjohann
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Cell Reports
Subjects:
CP: Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723007350

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http://www.sciencedirect.com/science/article/pii/S2211124723007350

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