Surface engineering Salmonella with pH‐responsive polyserotonin and self‐activated DNAzyme for better microbial therapy of tumor

Abstract Bacteria‐based microbial immunotherapy shows various unique properties for tumor therapy owing to their active tropism to tumor and multiple anti‐tumor mechanisms. However, its clinical benefit is far from satisfactory, which is limited by rapid systemic clearance and neutrophils‐mediated i...

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Bibliographic Details
Main Authors: Lina Guo, Hao Chen, Jinsong Ding, Pengfei Rong, Ming Sun, Wenhu Zhou
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Exploration
Subjects:
Online Access:https://doi.org/10.1002/EXP.20230017