Surface engineering Salmonella with pH‐responsive polyserotonin and self‐activated DNAzyme for better microbial therapy of tumor
Abstract Bacteria‐based microbial immunotherapy shows various unique properties for tumor therapy owing to their active tropism to tumor and multiple anti‐tumor mechanisms. However, its clinical benefit is far from satisfactory, which is limited by rapid systemic clearance and neutrophils‐mediated i...
Main Authors: | Lina Guo, Hao Chen, Jinsong Ding, Pengfei Rong, Ming Sun, Wenhu Zhou |
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Format: | Article |
Language: | English |
Published: |
Wiley
2023-12-01
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Series: | Exploration |
Subjects: | |
Online Access: | https://doi.org/10.1002/EXP.20230017 |
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