Synthesis of Dolichols in <i>Candida albicans</i> Is Co-Regulated with Elongation of Fatty Acids

Synthesis of Dolichols in <i>Candida albicans</i> Is Co-Regulated with Elongation of Fatty Acids

Protein glycosylation requires dolichyl phosphate as a carbohydrate carrier. Dolichols are α-saturated polyprenols, and their saturation in <i>S. cerevisiae</i> is catalyzed by polyprenyl reductase Dfg10 together with some other unknown enzymes. The aim of this study was to identify such...

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Bibliographic Details
Main Authors: Anna Janik, Urszula Perlińska-Lenart, Katarzyna Gawarecka, Justyna Augustyniak, Ewelina Bratek-Gerej, Przemysław Bernat, Sebastian Piłsyk, Patrycja Skalmowska, Grażyna Palamarczyk, Ewa Swiezewska, Joanna S. Kruszewska
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Candida albicans</i>
Tsc13 <i>trans</i>-2 enoyl-CoA reductase
Dfg10 polyprenyl reductase
Online Access:https://www.mdpi.com/1422-0067/23/1/409

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https://www.mdpi.com/1422-0067/23/1/409

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