Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites

Shear stress switches the association of endothelial enhancers from ETV/ETS to KLF transcription factor binding sites

Abstract Endothelial cells (ECs) lining blood vessels are exposed to mechanical forces, such as shear stress. These forces control many aspects of EC biology, including vascular tone, cell migration and proliferation. Despite a good understanding of the genes responding to shear stress, our insight...

Full description

Bibliographic Details
Main Authors: Roman Tsaryk, Nora Yucel, Elvin V. Leonard, Noelia Diaz, Olga Bondareva, Maria Odenthal-Schnittler, Zoltan Arany, Juan M. Vaquerizas, Hans Schnittler, Arndt F. Siekmann
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-08645-8

Internet

https://doi.org/10.1038/s41598-022-08645-8

Similar Items