Influencing factors and strategies of enhancing nanoparticles into tumors in vivo

Influencing factors and strategies of enhancing nanoparticles into tumors in vivo

The administration of nanoparticles (NPs) first faces the challenges of evading renal filtration and clearance of reticuloendothelial system (RES). After that, NPs infiltrate through the expanded endothelial space and penetrated the dense stroma of tumor microenvironment to tumor cells. As long as p...

Full description

Bibliographic Details
Main Authors: Mingming Zhang, Shan Gao, Dongjuan Yang, Yan Fang, Xiaojie Lin, Xuechao Jin, Yuli Liu, Xiu Liu, Kexin Su, Kai Shi
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Nanoparticles
Drug delivery
Reticuloendothelial system
Tumor microenvironment
Tumor stroma
Cancer-associated fibroblasts
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383521001052

Internet

http://www.sciencedirect.com/science/article/pii/S2211383521001052

Similar Items