Signs of Deregulated Gene Expression Are Present in Both CD14+ and CD14- PBMC From Non-Obese Men With Family History of T2DM

Signs of Deregulated Gene Expression Are Present in Both CD14+ and CD14- PBMC From Non-Obese Men With Family History of T2DM

AimDevelopment of type 2 diabetes (T2DM) is associated with disturbances in immune and metabolic status that may be reflected by an altered gene expression profile of peripheral blood mononuclear cells (PBMC). To reveal a potential family predisposition to these alterations, we investigated the regu...

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Bibliographic Details
Main Authors: Michal Koc, Michaela Šiklová, Veronika Šrámková, Marek Štěpán, Eva Krauzová, Vladimír Štich, Lenka Rossmeislová
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Endocrinology
Subjects:
oral glucose tolerance test
first-degree relatives
gene expression
peripheral blood mononuclear cells
type 2 diabetes mellitus
CD14− cells
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2020.582732/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2020.582732/full

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