HOXD9/miR-451a/PSMB8 axis is implicated in the regulation of cell proliferation and metastasis via PI3K/AKT signaling pathway in human anaplastic thyroid carcinoma

HOXD9/miR-451a/PSMB8 axis is implicated in the regulation of cell proliferation and metastasis via PI3K/AKT signaling pathway in human anaplastic thyroid carcinoma

Abstract Anaplastic thyroid carcinoma (ATC) is a deadly disease with a poor prognosis. Thus, there is a pressing need to determine the mechanism of ATC progression. The homeobox D9 (HOXD9) transcription factor has been associated with numerous malignancies but its role in ATC is unclear. In the pres...

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Bibliographic Details
Main Authors: Yong Zhong, Fan Yu, Ling Yang, Yu Wang, Lin Liu, Chengyou Jia, Haidong Cai, Jianshe Yang, Shiyang Sheng, Zhongwei Lv, Li Weng, Bo Wu, Xiaoping Zhang
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Anaplastic thyroid carcinoma
HOXD9
miR-451a
PSMB8
Metastasis
Proliferation
Online Access:https://doi.org/10.1186/s12967-023-04538-0

Internet

https://doi.org/10.1186/s12967-023-04538-0

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