Immunogenicity and protective activity of mRNA vaccine candidates against yellow fever virus in animal models

Abstract Despite the success of the widely used attenuated yellow fever (YF) vaccine, its global supply remains a substantial barrier to implementing vaccination campaigns in endemic regions and combating emerging epidemics. In A129 mice and rhesus macaques, we evaluated the immunogenicity and prote...

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Bibliographic Details
Main Authors: Lex G. Medina-Magües, Janine Mühe, Edith Jasny, Emily S. Medina-Magües, Nicole Roth, Jaime Lopera-Madrid, Cristhian Salas-Quinchucua, Cole Knuese, Benjamin Petsch, Jorge E. Osorio
Format: Article
Language:English
Published: Nature Portfolio 2023-03-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-023-00629-7