Coupling an artificial receptor with macrophage membrane for targeted and synergistic treatment of cholestasis
Cholestasis is defined as an impairment of bile acid flow leading to intrahepatic retention of toxic bile acids (BAs), which induce apoptosis or necrosis of hepatocytes and liver inflammation. Ursodeoxycholic acid (UDCA), a FDA-approved drug to treat cholestasis, has limited therapeutic effects due...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2022-12-01
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| Series: | Supramolecular Materials |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667240522000137 |