A clinically-relevant mouse model that displays hemorrhage exacerbates tourniquet-induced acute kidney injury

A clinically-relevant mouse model that displays hemorrhage exacerbates tourniquet-induced acute kidney injury

Hemorrhage is a leading cause of death in trauma. Tourniquets are effective at controlling extremity hemorrhage and have saved lives. However, tourniquets can cause ischemia reperfusion injury of limbs, leading to systemic inflammation and other adverse effects, which results in secondary damage to...

Full description

Bibliographic Details
Main Authors: Balamurugan Packialakshmi, David M. Burmeister, Joseph A. Anderson, Judah Morgan, Georgetta Cannon, Juliann G. Kiang, Yuanyi Feng, Sang Lee, Ian J. Stewart, Xiaoming Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Physiology
Subjects:
lower limb
ischemia/reperfusion
rhabdomyolysis
systemic inflammation
lung injury
liver injury
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1240352/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1240352/full

Similar Items