In Silico Quantification of Intersubject Variability on Aerosol Deposition in the Oral Airway

The extrathoracic oral airway is not only a major mechanical barrier for pharmaceutical aerosols to reach the lung but also a major source of variability in lung deposition. Using computational fluid dynamics, deposition of 1–30 µm particles was predicted in 11 CT-based models of the oral airways of...

Full description

Bibliographic Details
Main Authors: Azadeh A. T. Borojeni, Wanjun Gu, Bahman Asgharian, Owen Price, Andrew P. Kuprat, Rajesh K. Singh, Sean Colby, Richard A. Corley, Chantal Darquenne
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/15/1/160