ANGPTL4 functions as an oncogene through regulation of the ETV5/CDH5/AKT/MMP9 axis to promote angiogenesis in ovarian cancer

ANGPTL4 functions as an oncogene through regulation of the ETV5/CDH5/AKT/MMP9 axis to promote angiogenesis in ovarian cancer

Abstract Background Angiopoietin-like 4 (ANGPTL4) is highly expressed in a variety of neoplasms and promotes cancer progression. Nevertheless, the mechanism of ANGPTL4 in ovarian cancer (OC) metastasis remains unclear. This study aimeds to explore whether ANGPTL4 regulates OC progression and elucida...

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Bibliographic Details
Main Authors: Yinping Liu, Rui Yang, Yan Zhang, Yaping Zhu, Wei Bao
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Ovarian Research
Subjects:
ANGPTL4
Ovarian cancer
Angiogenesis
CDH5
Online Access:https://doi.org/10.1186/s13048-022-01060-7

Internet

https://doi.org/10.1186/s13048-022-01060-7

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