Rpl3l gene deletion in mice reduces heart weight over time

Rpl3l gene deletion in mice reduces heart weight over time

Introduction: The ribosomal protein L3-like (RPL3L) is a heart and skeletal muscle-specific ribosomal protein and paralogue of the more ubiquitously expressed RPL3 protein. Mutations in the human RPL3L gene are linked to childhood cardiomyopathy and age-related atrial fibrillation, yet the function...

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Bibliographic Details
Main Authors: Kelly M. Grimes, Vikram Prasad, Jiuzhou Huo, Yasuhide Kuwabara, Davy Vanhoutte, Tanya A. Baldwin, Stephanie L. K. Bowers, Anne Katrine Z. Johansen, Michelle A. Sargent, Suh-Chin J. Lin, Jeffery D. Molkentin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Physiology
Subjects:
heart
ribosome
translation
hypertrophy
gene expression
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1054169/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2023.1054169/full

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