Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan

Characterisation of drug-resistant Mycobacterium tuberculosis mutations and transmission in Pakistan

Abstract Tuberculosis, caused by Mycobacterium tuberculosis, is a high-burden disease in Pakistan, with multi-drug (MDR) and extensive-drug (XDR) resistance, complicating infection control. Whole genome sequencing (WGS) of M. tuberculosis is being used to infer lineages (strain-types), drug resistan...

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Bibliographic Details
Main Authors: Gary Napier, Anwar Sheed Khan, Abdul Jabbar, Muhammad Tahir Khan, Sajid Ali, Muhammad Qasim, Noor Mohammad, Rumina Hasan, Zahra Hasan, Susana Campino, Sajjad Ahmad, Baharullah Khattak, Simon J. Waddell, Taj Ali Khan, Jody E. Phelan, Taane G. Clark
Format: Article
Language:English
Published: Nature Portfolio 2022-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-11795-4

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https://doi.org/10.1038/s41598-022-11795-4

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