Opening a Can of Worms: Leprosy Reactions and Complicit Soil-Transmitted Helminths

Background: >94% of new annual leprosy cases are diagnosed in populations co-endemic for soil-transmitted helminths (STH). STH can profoundly dysregulate host immune responses towards Th2 bias, which can be restored over time after deworming. We hypothesize that STH co-infection is associated wit...

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Bibliographic Details
Main Authors: Deanna A. Hagge, Pawan Parajuli, Chhatra B. Kunwar, Divya R.S.J.B. Rana, Ruby Thapa, Kapil D. Neupane, Peter Nicholls, Linda B. Adams, Annemieke Geluk, Mahesh Shah, Indra B. Napit
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:EBioMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417303432