Simple Nanoparticles from the Assembly of Cationic Polymer and Antigen as Immunoadjuvants

Simple Nanoparticles from the Assembly of Cationic Polymer and Antigen as Immunoadjuvants

Since antigens are negatively charged, they combine well with positively charged adjuvants. Here, ovalbumin (OVA) (0.1 mg&#183;mL<sup>&#8722;1</sup>) and poly (diallyldimethylammonium chloride) (PDDA) (0.01 mg&#183;mL<sup>&#8722;1</sup>) yielded PDDA/OVA assem...

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Bibliographic Details
Main Authors: Yunys Pérez-Betancourt, Bianca de Carvalho Lins Fernandes Távora, Mônica Colombini, Eliana L. Faquim-Mauro, Ana Maria Carmona-Ribeiro
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Vaccines
Subjects:
cationic polymer
poly (diallyldimethylammonium chloride)
model antigen
ovalbumin
antigen/cationic polymer nanoparticles
poly-cation cytotoxicity
dynamic light scattering
scanning electron microscopy
elisa assays
delayed-type hypersensitivity assay
Online Access:https://www.mdpi.com/2076-393X/8/1/105

Internet

https://www.mdpi.com/2076-393X/8/1/105

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