β-Hydroxy β-methylbutyrate improves dexamethasone-induced muscle atrophy by modulating the muscle degradation pathway in SD rat.

β-Hydroxy β-methylbutyrate improves dexamethasone-induced muscle atrophy by modulating the muscle degradation pathway in SD rat.

Skeletal muscle atrophy results from various conditions including high levels of glucocorticoids, and β-hydroxy β-methylbutyrate (HMB; a metabolite of leucine) is a potent therapeutical supplement used to treat various muscle disorders. Recent studies have demonstrated that HMB inhibits dexamethason...

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Bibliographic Details
Main Authors: Kyung Kyun Noh, Ki Wung Chung, Yeon Ja Choi, Min Hi Park, Eun Ji Jang, Chan Hum Park, Changshin Yoon, Nam Deuk Kim, Mi Kyung Kim, Hae Young Chung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4102592?pdf=render

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http://europepmc.org/articles/PMC4102592?pdf=render

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