Molecular characterization of Plasmodium falciparum DNA-3-methyladenine glycosylase

Molecular characterization of Plasmodium falciparum DNA-3-methyladenine glycosylase

Abstract Background The emergence of artemisinin-resistant malaria parasites highlights the need for novel drugs and their targets. Alkylation of purine bases can hinder DNA replication and if unresolved would eventually result in cell death. DNA-3-methyladenine glycosylase (MAG) is responsible for...

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Bibliographic Details
Main Authors: Nattapon Pinthong, Paviga Limudomporn, Jitlada Vasuvat, Poom Adisakwattana, Pongruj Rattaprasert, Porntip Chavalitshewinkoon-Petmitr
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
DNA-3-methyladenine glycosylase
DNA repair
Malaria
Online Access:http://link.springer.com/article/10.1186/s12936-020-03355-w

Internet

http://link.springer.com/article/10.1186/s12936-020-03355-w

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