Role of bone marrow-derived fibroblasts in renal fibrosis

Renal fibrosis represents a common pathway leading to progression of chronic kidney disease. Renal interstitial fibrosis is characterized by extensive fibroblast activation and excessive production and deposition of extracellular matrix (ECM), which leads to progressive loss of kidney function. Ther...

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Bibliographic Details
Main Authors: Jingyin eYan, Zhengmao eZhang, Li eJia, Yanlin eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2016.00061/full