Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic rats

Artesunate-loaded thermosensitive chitosan hydrogel promotes osteogenesis of maxillary tooth extraction through regulating T lymphocytes in type 2 diabetic rats

Abstract Background Type 2 diabetes mellitus (T2DM) causes severe bone loss after tooth extraction as a hyperglycemic environment causes aberrant bone homeostasis. Artesunate (ART) is known to possess anti-inflammation and osteogenic properties. However, its osteogenesis property in alveolar bone re...

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Bibliographic Details
Main Authors: Jinghong Luo, Chen Liang, Kun Chen, Kai Zeng, Rui Bai, Chan Tang, Jiaquan Li, Xiaolin Nong
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Oral Health
Subjects:
Artesunate
Hydrogel
Type 2 diabetes mellitus
Osteogenesis
Mitogen-activated protein kinase kinases
Online Access:https://doi.org/10.1186/s12903-024-04127-7

Internet

https://doi.org/10.1186/s12903-024-04127-7

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