Hydrogen sulfide donor-based fibrates: Design, synthesis, and evaluation for hypolipidemic activity and hepatoprotection
Novel hydrogen sulfide donor-based fibrate derivatives were synthesized and assessed for hypolipidemic and hepatoprotective effects in Triton WR-1339-induced hyperlipidemic mice. After preliminary screening of the target compounds, T5 exhibited significant hypolipidemic effects, reducing triglycerid...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-06-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715624003047 |