Progranulin modulates zebrafish motoneuron development <it>in vivo </it>and rescues truncation defects associated with knockdown of Survival motor neuron 1
<p>Abstract</p> <p>Background</p> <p>Progranulin (PGRN) encoded by the <it>GRN </it>gene, is a secreted glycoprotein growth factor that has been implicated in many physiological and pathophysiological processes. PGRN haploinsufficiency caused by autosomal do...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2010-10-01
|
| Series: | Molecular Neurodegeneration |
| Online Access: | http://www.molecularneurodegeneration.com/content/5/1/41 |