Structural Features of Heparan Sulfate from Multiple Osteochondromas and Chondrosarcomas

Structural Features of Heparan Sulfate from Multiple Osteochondromas and Chondrosarcomas

Multiple osteochondromas (MO) is a hereditary disorder associated with benign cartilaginous tumors, known to be characterized by absence or highly reduced amount of heparan sulfate (HS) in the extracellular matrix of growth plate cartilage, which alters proper signaling networks leading to improper...

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Bibliographic Details
Main Authors: Noemi Veraldi, Alessandro Parra, Elena Urso, Cesare Cosentino, Manuela Locatelli, Serena Corsini, Elena Pedrini, Annamaria Naggi, Antonella Bisio, Luca Sangiorgi
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Molecules
Subjects:
heparan sulfate
multiple osteochondromas (MO)
peripheral chondrosarcoma
human cartilage
NMR
HPLC–MS
EXT
Online Access:https://www.mdpi.com/1420-3049/23/12/3277

Internet

https://www.mdpi.com/1420-3049/23/12/3277

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