An ancestral fold reveals the evolutionary link between RNA polymerase and ribosomal proteins

Abstract Numerous molecular machines are required to drive the central dogma of molecular biology. However, the means by which these numerous proteins emerged in the early evolutionary stage of life remains enigmatic. Many of them possess small β-barrel folds with different topologies, represented b...

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Detalhes bibliográficos
Principais autores: Sota Yagi, Shunsuke Tagami
Formato: Artigo
Idioma:English
Publicado em: Nature Portfolio 2024-07-01
coleção:Nature Communications
Acesso em linha:https://doi.org/10.1038/s41467-024-50013-9