An RNAi based screen in Drosophila larvae identifies fascin as a regulator of myoblast fusion and myotendinous junction structure

An RNAi based screen in Drosophila larvae identifies fascin as a regulator of myoblast fusion and myotendinous junction structure

Abstract Background A strength of Drosophila as a model system is its utility as a tool to screen for novel regulators of various functional and developmental processes. However, the utility of Drosophila as a screening tool is dependent on the speed and simplicity of the assay used. Methods Here, w...

Full description

Bibliographic Details
Main Authors: Jaclyn M. Camuglia, Torrey R. Mandigo, Richard Moschella, Jenna Mark, Christine H. Hudson, Derek Sheen, Eric S. Folker
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Skeletal Muscle
Subjects:
Nuclear movement
Drosophila
Myoblast fusion
Myotendinous junction
Fascin
Myogenesis
Online Access:http://link.springer.com/article/10.1186/s13395-018-0159-9

Internet

http://link.springer.com/article/10.1186/s13395-018-0159-9

Similar Items