Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice

Splicing factor SRSF1 is essential for homing of precursor spermatogonial stem cells in mice

Spermatogonial stem cells (SSCs) are essential for continuous spermatogenesis and male fertility. The underlying mechanisms of alternative splicing (AS) in mouse SSCs are still largely unclear. We demonstrated that SRSF1 is essential for gene expression and splicing in mouse SSCs. Crosslinking immun...

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Bibliographic Details
Main Authors: Longjie Sun, Zheng Lv, Xuexue Chen, Rong Ye, Shuang Tian, Chaofan Wang, Xiaomei Xie, Lu Yan, Xiaohong Yao, Yujing Shao, Sheng Cui, Juan Chen, Jiali Liu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-01-01
Series:eLife
Subjects:
SRSF1
alternative splicing
Sertoli cell-only syndrome
infertility
precursor spermatogonial stem cells
homing of precursor SSCs
Online Access:https://elifesciences.org/articles/89316

Internet

https://elifesciences.org/articles/89316

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