Molecular and Pathological Profiling of Corresponding Treatment-Naïve and Neoadjuvant Pazopanib-Treated High-Risk Soft Tissue Sarcoma Samples of the GISG-04/NOPASS Study

Molecular and Pathological Profiling of Corresponding Treatment-Naïve and Neoadjuvant Pazopanib-Treated High-Risk Soft Tissue Sarcoma Samples of the GISG-04/NOPASS Study

In the framework of the German Interdisciplinary Sarcoma Group GISG-04/NOPASS trial, we evaluated soft tissue sarcoma samples taken before and after neoadjuvant pazopanib therapy using histopathology and next generation sequencing (NGS) to find potential predictive biomarkers. We also aimed to impro...

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Bibliographic Details
Main Authors: Timo Gaiser, Christian Sauer, Alexander Marx, Jens Jakob, Bernd Kasper, Peter Hohenberger, Daniela Hirsch, Ulrich Ronellenfitsch
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biology
Subjects:
soft tissue sarcoma
STS
pazopanib
next generation sequencing
NGS
CDK4
Online Access:https://www.mdpi.com/2079-7737/10/7/639

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https://www.mdpi.com/2079-7737/10/7/639

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