Meta-analysis of set-based multiple phenotype association test based on GWAS summary statistics from different cohorts

Meta-analysis of set-based multiple phenotype association test based on GWAS summary statistics from different cohorts

Genome-wide association studies (GWAS) have emerged as popular tools for identifying genetic variants that are associated with complex diseases. Standard analysis of a GWAS involves assessing the association between each variant and a disease. However, this approach suffers from limited reproducibil...

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Bibliographic Details
Main Authors: Lirong Zhu, Shuanglin Zhang, Qiuying Sha
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-09-01
Series:Frontiers in Genetics
Subjects:
meta-analysis
joint analyses of multiple phenotypes
set-based association tests
GWAS summary statistics
phenotype simulator
multiple GWAS cohorts
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2024.1359591/full

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https://www.frontiersin.org/articles/10.3389/fgene.2024.1359591/full

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