Purkinje cell axonal swellings enhance action potential fidelity and cerebellar function

Purkinje cell axonal swellings enhance action potential fidelity and cerebellar function

Axonal swellings have been found on Purkinje cell axons in the cerebellum both during development and disease. The authors show that axons with swellings propagate action potentials with higher fidelity than those without and that mice with more axonal swellings learn cerebellar-related tasks better...

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Bibliographic Details
Main Authors: Daneck Lang-Ouellette, Kim M. Gruver, Amy Smith-Dijak, François G. C. Blot, Chloe A. Stewart, Pauline de Vanssay de Blavous, Connie H. Li, Carter Van Eitrem, Charlotte Rosen, Phyllis L. Faust, Martijn Schonewille, Alanna J. Watt
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24390-4

Internet

https://doi.org/10.1038/s41467-021-24390-4

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