Dual Targeting of PI3K and HDAC by CUDC-907 Inhibits Pediatric Neuroblastoma Growth

The dysregulation of PI3K, HDACs, and MYCN are well known for promoting multiple cancer types, including neuroblastoma (NB). Targeting the upstream regulators of MYCN, including HDACs and PI3K, was shown to suppress cancer growth. In the present study, we analyze different NB patient datasets to rev...

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Bibliographic Details
Main Authors: Rameswari Chilamakuri, Saurabh Agarwal
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/4/1067