A novel patient-derived immortalised cell line of myxofibrosarcoma: a tool for preclinical drugs testing and the generation of near-patient models

A novel patient-derived immortalised cell line of myxofibrosarcoma: a tool for preclinical drugs testing and the generation of near-patient models

Abstract Background Myxofibrosarcoma is a rare malignant soft tissue sarcoma characterised by multiple local recurrence and can become of higher grade with each recurrence. Consequently, myxofibrosarcoma represents a burden for patients, a challenge for clinicians, and an interesting disease to stud...

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Bibliographic Details
Main Authors: Ania Naila Guerrieri, Chiara Bellotti, Marianna Penzo, Marta Columbaro, Micaela Pannella, Alessandro De Vita, Marco Gambarotti, Laura Mercatali, Roberta Laranga, Barbara Dozza, Silvia Vanni, Serena Corsini, Tommaso Frisoni, Giacomo Miserocchi, Toni Ibrahim, Enrico Lucarelli
Format: Article
Language:English
Published: BMC 2023-12-01
Series:BMC Cancer
Subjects:
Myxofibrosarcoma
Soft Tissue Sarcoma
Preclinical models
3D cell culture
Chorioallantoic membrane (CAM)
Online Access:https://doi.org/10.1186/s12885-023-11658-9

Internet

https://doi.org/10.1186/s12885-023-11658-9

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