Correlation between NGS panel-based mutation results and clinical information in colorectal cancer patients

Correlation between NGS panel-based mutation results and clinical information in colorectal cancer patients

Early mutation identification guides patients with colorectal cancer (CRC) toward targeted therapies. In the present study, 414 patients with CRC were enrolled, and amplicon-based targeted next-generation sequencing (NGS) was then performed to detect genomic alterations within the 73 cancer-related...

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Bibliographic Details
Main Authors: Bo Cheng, Lin Xu, Yunzhi Zhang, Huimin Yang, Shan Liu, Shanshan Ding, Huan Zhao, Yi Sui, Chan Wang, Lanju Quan, Jinhong Liu, Ye Liu, Hongming Wang, Zhaoqing Zheng, Xizhao Wu, Jing Guo, Zhaohong Wen, Ruya Zhang, Fei Wang, Hongmei Liu, Suozhu Sun
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Heliyon
Subjects:
Colorectal cancer
Next-generation sequencing
gene mutation
microsatellite instability
Molecular targeted therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024053301

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http://www.sciencedirect.com/science/article/pii/S2405844024053301

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