Evaluating α-galactosylceramide as an adjuvant for live attenuated influenza vaccines in pigs

Evaluating α-galactosylceramide as an adjuvant for live attenuated influenza vaccines in pigs

Abstract Natural killer T (NKT) cells activated with the glycolipid ligand α-galactosylceramide (α-GalCer) stimulate a wide variety of immune cells that enhance vaccine-mediated immune responses. Several studies have used this approach to adjuvant inactivated and subunit influenza A virus (IAV) vacc...

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Bibliographic Details
Main Authors: Bianca L. Artiaga, Igor Morozov, Russell Ransburgh, Taeyong Kwon, Velmurugan Balaraman, Sabarish V. Indran, Darling Melany De Carvalho Madrid, Weihong Gu, Jamie Henningson, Wenjun Ma, Jürgen A. Richt, John P. Driver
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Animal Diseases
Subjects:
Natural killer T cell
Influenza A virus
Vaccine
Live attenuated influenza virus
Adjuvant
α-Galactosylceramide
Online Access:https://doi.org/10.1186/s44149-022-00051-x

Internet

https://doi.org/10.1186/s44149-022-00051-x

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