Stimulated mast cells promote maturation of myocardial microvascular endothelial cell neovessels by modulating the angiopoietin-Tie-2 signaling pathway

Angiopoietin (Ang)-1 and Ang-2 interact in angiogenesis to activate the Tie-2 receptor, which may be involved in new vessel maturation and regression. Mast cells (MCs) are also involved in formation of new blood vessels and angiogenesis. The present study was designed to test whether MCs can mediate...

Full description

Bibliographic Details
Main Authors: Z.H. Wang, W. Zhu, J.P. Tao, Q.Y. Zhang, M. Wei
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-11-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013001100920&lng=en&tlng=en