Expanding uncapped translation and emerging function of circular RNA in carcinomas and noncarcinomas

Abstract Circular RNAs (circRNAs) are classified as noncoding RNAs because they are devoid of a 5’ end cap and a 3’ end poly (A) tail necessary for cap-dependent translation. However, increasing numbers of translated circRNAs identified through high-throughput RNA sequencing overlapping with polysom...

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Bibliographic Details
Main Authors: Yan Wang, Chunjie Wu, Yu Du, Zhongwei Li, Minle Li, Pingfu Hou, Zhigang Shen, Sufang Chu, Junnian Zheng, Jin Bai
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Molecular Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12943-021-01484-7